An examination of the cutoff value of the depth of invasion for prophylactic neck dissection in stage I/II tongue cancer.
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| Title: | An examination of the cutoff value of the depth of invasion for prophylactic neck dissection in stage I/II tongue cancer. |
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| Authors: | Terada, Hoshino (AUTHOR), Sasaki, Eiichi (AUTHOR), Suzuki, Hidenori (AUTHOR), Nishikawa, Daisuke (AUTHOR), Beppu, Shintaro (AUTHOR), Hanai, Nobuhiro (AUTHOR) |
| Source: | Acta Oto-Laryngologica. May2020, Vol. 140 Issue 5, p422-426. 5p. |
| Subjects: | Cancer invasiveness, Statistical correlation, Lymph nodes, Magnetic resonance imaging, Preventive medicine, Neck surgery, Surgery, Tumors, Tumor classification, Tongue tumors, Cancer of unknown primary origin, Treatment effectiveness |
| Abstract (English): | Background: In stage-I/stage-II oral tongue cancer, the cutoff value of depth of invasion (DOI) for prophylactic neck dissection is controversial. Objectives: To examine the relationship between the DOI and the rate of occult lymph node metastasis. In addition, to examine the relationship between the DOI evaluated by magnetic resonance imaging (MRI) and pathological DOI. Materials and methods: In this retrospective study, 95 patients with clinical T1-2/N0M0 oral tongue cancer were enrolled. The rate of occult lymph node metastasis per DOI between 2 and 11 mm was calculated from the total pathological lymph node metastasis and delayed neck metastasis cases. We measured DOI using MRI and compared DOI obtained from pathology. Results: The total rate of occult lymph node metastasis was 23.9%. In the rate of occult lymph node metastasis per DOI, there were two peaks at point of 5 to 6 mm and 9 to 10 mm. And there was a significant correlation between the DOI evaluated by MRI and the pathological DOI (Pearson's correlation coefficient was 0.87). Conclusions and significance: There was no consistent increase in the rate of occult lymph node metastasis per DOI. MRI was a useful modality to measure the DOI. [ABSTRACT FROM AUTHOR] |
| Abstract (Chinese): | 背景：在一期/二期舌癌中, 浸润深度（DOI）作为预防性颈清扫的临界值仍存在争议。 目的：探讨DOI与隐匿性淋巴结转移率的关系。此外, 探讨通过磁共振成像（MRI）得出的DOI与病理DOI的关系。 材料与方法：回顾性分析95例T1-2/N0M0舌癌患者的临床资料。根据病理性淋巴结转移和颈部延迟转移病例计算, 得出每2-11毫米之间的DOI隐匿淋巴结转移率。我们用MRI测量DOI, 并将其与病理结果相比。 结果：隐匿性淋巴结转移率为23.9%。在每个DOI的隐匿淋巴结转移率中, 在5-6 mm和9-10 mm处出现两个高峰。MRI得出的DOI与病理DOI有显著相关性（Pearson相关系数为0.87）。 结论及意义：每个DOI的隐匿淋巴结转移率并不是一直增加的。MRI是测量DOI的有效手段。 [ABSTRACT FROM AUTHOR] |
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| Database: | Psychology and Behavioral Sciences Collection |
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| Abstract: | Background: In stage-I/stage-II oral tongue cancer, the cutoff value of depth of invasion (DOI) for prophylactic neck dissection is controversial. Objectives: To examine the relationship between the DOI and the rate of occult lymph node metastasis. In addition, to examine the relationship between the DOI evaluated by magnetic resonance imaging (MRI) and pathological DOI. Materials and methods: In this retrospective study, 95 patients with clinical T1-2/N0M0 oral tongue cancer were enrolled. The rate of occult lymph node metastasis per DOI between 2 and 11 mm was calculated from the total pathological lymph node metastasis and delayed neck metastasis cases. We measured DOI using MRI and compared DOI obtained from pathology. Results: The total rate of occult lymph node metastasis was 23.9%. In the rate of occult lymph node metastasis per DOI, there were two peaks at point of 5 to 6 mm and 9 to 10 mm. And there was a significant correlation between the DOI evaluated by MRI and the pathological DOI (Pearson's correlation coefficient was 0.87). Conclusions and significance: There was no consistent increase in the rate of occult lymph node metastasis per DOI. MRI was a useful modality to measure the DOI. [ABSTRACT FROM AUTHOR] |
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| ISSN: | 00016489 |
| DOI: | 10.1080/00016489.2020.1717606 |
