Recruitment into a Clinical Trial of People Living with Uncontrolled HIV Infection Who Inject Drugs: a Site Case Report from the CTN 67 CHOICES Study.
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| Title: | Recruitment into a Clinical Trial of People Living with Uncontrolled HIV Infection Who Inject Drugs: a Site Case Report from the CTN 67 CHOICES Study. |
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| Authors: | Tookes, Hansel (AUTHOR), Ucha, Jessica (AUTHOR), Rodriguez, Allan E. (AUTHOR), Suarez, Edward (AUTHOR), Alonso, Elizabeth (AUTHOR), Metsch, Lisa R. (AUTHOR), Feaster, Daniel J. (AUTHOR), Bartholomew, Tyler S. (AUTHOR), Hoffman, Kim A. (AUTHOR), Korthuis, P. Todd (AUTHOR) |
| Source: | Journal of Behavioral Health Services & Research. Apr2022, Vol. 49 Issue 2, p240-251. 12p. |
| Subjects: | HIV-positive persons, Needle exchange programs, Human research subjects, Acquisition of data methodology, Patient selection, Attitudes of medical personnel, Research methodology, Interviewing, Randomized controlled trials, Patients' attitudes, Medical records, Interprofessional relations, Thematic analysis |
| Geographic Terms: | Florida |
| Abstract: | CHOICES was an open-label, randomized, comparative effectiveness trial of office-based extended-release naltrexone versus treatment as usual in people with untreated opioid use disorder and HIV. This study explored facilitators to recruitment in Miami, a successful recruiting site in the national trial. The mixed-methods study included quantitative surveys of randomized participants, medical record abstraction, and qualitative interviews with study staff. Miami recruited 47 (40.5%) of 116 randomized participants in the six-site national trial. In-depth interviews of study staff (n = 6) revealed that Miami had a recruitment approach consisting of street level outreach and a close relationship with the local syringe services program (SSP). Partnership with a local SSP provided access to people living with HIV who inject drugs in Miami. SSPs' fundamental trust within the community of people who inject drugs can be leveraged in studies aiming to improve health outcomes in this underserved and high-priority population. [ABSTRACT FROM AUTHOR] |
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| Database: | Psychology and Behavioral Sciences Collection |
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| Abstract: | CHOICES was an open-label, randomized, comparative effectiveness trial of office-based extended-release naltrexone versus treatment as usual in people with untreated opioid use disorder and HIV. This study explored facilitators to recruitment in Miami, a successful recruiting site in the national trial. The mixed-methods study included quantitative surveys of randomized participants, medical record abstraction, and qualitative interviews with study staff. Miami recruited 47 (40.5%) of 116 randomized participants in the six-site national trial. In-depth interviews of study staff (n = 6) revealed that Miami had a recruitment approach consisting of street level outreach and a close relationship with the local syringe services program (SSP). Partnership with a local SSP provided access to people living with HIV who inject drugs in Miami. SSPs' fundamental trust within the community of people who inject drugs can be leveraged in studies aiming to improve health outcomes in this underserved and high-priority population. [ABSTRACT FROM AUTHOR] |
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| ISSN: | 10943412 |
| DOI: | 10.1007/s11414-021-09771-3 |
