Self-reported sleep in relation to risk of dementia a quarter of a century later at age 90+: The 90+ Study.
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| Title: | Self-reported sleep in relation to risk of dementia a quarter of a century later at age 90+: The 90+ Study. |
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| Authors: | Melikyan, Zarui A. (AUTHOR), Kawas, Claudia H. (AUTHOR), Paganini-Hill, Annlia (AUTHOR), Jiang, Luohua (AUTHOR), Mander, Bryce A. (AUTHOR), Corrada, María M. (AUTHOR) |
| Source: | Behavioral Sleep Medicine. Sep/Oct2023, Vol. 21 Issue 5, p620-632. 13p. 1 Diagram, 3 Charts, 1 Graph. |
| Subjects: | Disease risk factors, Sleep duration, Naps (Sleep), Age, Confidence intervals |
| Abstract: | To examine sex-specific associations of sleep duration and napping self-reported at mean age of 69 years (range: 53–81) with risk of incident dementia 24 years later at age 90 +. Analytic sample included individuals from a population-based study who reported sleep and napping once in the 1980s and 24 years later (range: 16–38) joined The 90+ Study and were evaluated in-person. Those without dementia at baseline of The 90+ Study were prospectively followed. Hazard ratios [HR] and 95% confidence intervals [CI] of dementia risk were estimated by Cox regression. Of 574 participants 71% were women, mean age at start of dementia follow-up with The 90+ Study was 93 years (range: 90–102). After 3.3 years (range: 0.4–13.8) of follow-up 47% developed dementia. Higher risk of dementia at age 90+ was seen in women with <6 hours of self-reported sleep per night (adjusted HR = 2.00; 95% CI = 1.15–3.50; p =.01) compared with 8 hours. Lower risk of dementia at 90+ was seen in men with short-to-moderate (<60 minutes) self-reported naps compared with no naps (HR = 0.33; 95% CI = 0.18–0.63; p <.01). Sleep and nap 24 years earlier are important risk factors for dementia after age 90. [ABSTRACT FROM AUTHOR] |
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| Database: | Psychology and Behavioral Sciences Collection |
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| Abstract: | To examine sex-specific associations of sleep duration and napping self-reported at mean age of 69 years (range: 53–81) with risk of incident dementia 24 years later at age 90 +. Analytic sample included individuals from a population-based study who reported sleep and napping once in the 1980s and 24 years later (range: 16–38) joined The 90+ Study and were evaluated in-person. Those without dementia at baseline of The 90+ Study were prospectively followed. Hazard ratios [HR] and 95% confidence intervals [CI] of dementia risk were estimated by Cox regression. Of 574 participants 71% were women, mean age at start of dementia follow-up with The 90+ Study was 93 years (range: 90–102). After 3.3 years (range: 0.4–13.8) of follow-up 47% developed dementia. Higher risk of dementia at age 90+ was seen in women with <6 hours of self-reported sleep per night (adjusted HR = 2.00; 95% CI = 1.15–3.50; p =.01) compared with 8 hours. Lower risk of dementia at 90+ was seen in men with short-to-moderate (<60 minutes) self-reported naps compared with no naps (HR = 0.33; 95% CI = 0.18–0.63; p <.01). Sleep and nap 24 years earlier are important risk factors for dementia after age 90. [ABSTRACT FROM AUTHOR] |
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| ISSN: | 15402002 |
| DOI: | 10.1080/15402002.2022.2148668 |
