Effects of Participating in Religious Groups on Mental Health Issues: A Two-Sample Mendelian Randomization Study.

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Bibliographic Details
Title: Effects of Participating in Religious Groups on Mental Health Issues: A Two-Sample Mendelian Randomization Study.
Authors: Li, Hansen (AUTHOR), Zhang, Xing (AUTHOR), Cao, Yang (AUTHOR), Zhang, Guodong (AUTHOR)
Source: International Journal for the Psychology of Religion. 2024, Vol. 34 Issue 1, p24-36. 13p.
Subjects: Religious groups, Anxiety disorders, Suicide risk factors, Mental health, Sensitivity analysis
Geographic Terms: United Kingdom
Abstract: We conducted a Mendelian randomization study to evaluate the potential causal effects of attending religious groups on the prevalence of depression, generalized anxiety disorders, anxiety disorders, and suicide and self-harm. Data from the UK Biobank and the FinnGen project were processed by inverse variance weighting (IVW), weighted median, and MR-Egger regression methods. Despite certain pleiotropic risks, we found that attending religious groups was potentially associated with a reduced risk of anxiety disorders (OR = 0.213, p =.028). The pleiotropies were largely controlled and the effect on anxiety disorders became more significant in our sensitivity analysis (OR = 0.162; p =.006). Additionally, attending religious groups was associated with a reduced risk of suicide and self-harm (OR = 0.231, p =.0006). However, we did not observe any substantial protection against depression. In conclusion, our study adds to the existing literature and sheds light on the potential health benefits of religious activities from a novel perspective. [ABSTRACT FROM AUTHOR]
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Database: Psychology and Behavioral Sciences Collection
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Abstract:We conducted a Mendelian randomization study to evaluate the potential causal effects of attending religious groups on the prevalence of depression, generalized anxiety disorders, anxiety disorders, and suicide and self-harm. Data from the UK Biobank and the FinnGen project were processed by inverse variance weighting (IVW), weighted median, and MR-Egger regression methods. Despite certain pleiotropic risks, we found that attending religious groups was potentially associated with a reduced risk of anxiety disorders (OR = 0.213, p =.028). The pleiotropies were largely controlled and the effect on anxiety disorders became more significant in our sensitivity analysis (OR = 0.162; p =.006). Additionally, attending religious groups was associated with a reduced risk of suicide and self-harm (OR = 0.231, p =.0006). However, we did not observe any substantial protection against depression. In conclusion, our study adds to the existing literature and sheds light on the potential health benefits of religious activities from a novel perspective. [ABSTRACT FROM AUTHOR]
ISSN:10508619
DOI:10.1080/10508619.2023.2267956