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Silent substitution S-cone electroretinogram in subjects with diabetes mellitus.

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Title: Silent substitution S-cone electroretinogram in subjects with diabetes mellitus.
Authors: Mortlock, Katharine E., Chiti, Zohreh, Drasdo, Neville, Owens, David R., North, Rachel V.
Source: Ophthalmic & Physiological Optics. Sep2005, Vol. 25 Issue 5, p392-399. 8p.
Subjects: Diabetes, Electroretinography, Eye diseases, Glaucoma, Electrophysiology
Abstract: A defect in the blue sensitive mechanism has been reported in certain ocular and systemic diseases. For example, tritanopic colour vision defects and changes to the S-cone electroretinogram (ERG) have been demonstrated in glaucoma and diabetes mellitus. Electrophysiological methods of eliciting the S-cone ERG, however, often result in considerable L- and M-cone intrusion. We report the findings of a study employing the silent substitution S-cone ERG technique, which is thought to represent an almost pure S-cone signal, and the L'Anthony desaturated D15 colour vision test in subjects with Type 1 or 2 diabetes mellitus with no or minimal background retinopathy. The results of this study show a significantly increased S-cone ERG b-wave implicit time and significantly worse colour vision in those with background retinopathy compared with those with no diabetic retinopathy. This suggests that S-cone pathway dysfunction may be responsible for the deterioration in colour vision found in diabetes mellitus. [ABSTRACT FROM AUTHOR]
Copyright of Ophthalmic & Physiological Optics is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Silent substitution S-cone electroretinogram in subjects with diabetes mellitus.
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  Data: <searchLink fieldCode="AR" term="%22Mortlock%2C+Katharine+E%2E%22">Mortlock, Katharine E.</searchLink><br /><searchLink fieldCode="AR" term="%22Chiti%2C+Zohreh%22">Chiti, Zohreh</searchLink><br /><searchLink fieldCode="AR" term="%22Drasdo%2C+Neville%22">Drasdo, Neville</searchLink><br /><searchLink fieldCode="AR" term="%22Owens%2C+David+R%2E%22">Owens, David R.</searchLink><br /><searchLink fieldCode="AR" term="%22North%2C+Rachel+V%2E%22">North, Rachel V.</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22Ophthalmic+%26+Physiological+Optics%22">Ophthalmic & Physiological Optics</searchLink>. Sep2005, Vol. 25 Issue 5, p392-399. 8p.
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  Data: <searchLink fieldCode="DE" term="%22Diabetes%22">Diabetes</searchLink><br /><searchLink fieldCode="DE" term="%22Electroretinography%22">Electroretinography</searchLink><br /><searchLink fieldCode="DE" term="%22Eye+diseases%22">Eye diseases</searchLink><br /><searchLink fieldCode="DE" term="%22Glaucoma%22">Glaucoma</searchLink><br /><searchLink fieldCode="DE" term="%22Electrophysiology%22">Electrophysiology</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: A defect in the blue sensitive mechanism has been reported in certain ocular and systemic diseases. For example, tritanopic colour vision defects and changes to the S-cone electroretinogram (ERG) have been demonstrated in glaucoma and diabetes mellitus. Electrophysiological methods of eliciting the S-cone ERG, however, often result in considerable L- and M-cone intrusion. We report the findings of a study employing the silent substitution S-cone ERG technique, which is thought to represent an almost pure S-cone signal, and the L'Anthony desaturated D15 colour vision test in subjects with Type 1 or 2 diabetes mellitus with no or minimal background retinopathy. The results of this study show a significantly increased S-cone ERG b-wave implicit time and significantly worse colour vision in those with background retinopathy compared with those with no diabetic retinopathy. This suggests that S-cone pathway dysfunction may be responsible for the deterioration in colour vision found in diabetes mellitus. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Ophthalmic & Physiological Optics is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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      – Type: doi
        Value: 10.1111/j.1475-1313.2005.00299.x
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      – Code: eng
        Text: English
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        PageCount: 8
        StartPage: 392
    Subjects:
      – SubjectFull: Diabetes
        Type: general
      – SubjectFull: Electroretinography
        Type: general
      – SubjectFull: Eye diseases
        Type: general
      – SubjectFull: Glaucoma
        Type: general
      – SubjectFull: Electrophysiology
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      – TitleFull: Silent substitution S-cone electroretinogram in subjects with diabetes mellitus.
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            NameFull: Chiti, Zohreh
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            NameFull: Drasdo, Neville
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            NameFull: Owens, David R.
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            NameFull: North, Rachel V.
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            – D: 01
              M: 09
              Text: Sep2005
              Type: published
              Y: 2005
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              Value: 25
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