A New Antipsychotic for Schizophrenia: Xanomeline and Trospium (Cobenfy).

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Bibliographic Details
Title: A New Antipsychotic for Schizophrenia: Xanomeline and Trospium (Cobenfy).
Authors: Mills, Jeremy
Source: Issues in Mental Health Nursing. Dec2024, Vol. 45 Issue 12, p1364-1367. 4p.
Subjects: Drug therapy for schizophrenia, Combination drug therapy, Blood-brain barrier, Antipsychotic agents, United States. Food & Drug Administration, Drug approval, Pharmacy information services, Dopamine antagonists, Muscarinic antagonists, Drug development, Psychopharmacology, Muscarinic agonists, Therapeutics, Pharmacodynamics
Abstract: The article discusses the groundbreaking approval of a new antipsychotic medication, Cobenfy (xanomeline and trospium), which marks a significant shift in the treatment of schizophrenia by targeting acetylcholine instead of dopamine. This approval represents a major departure from traditional antipsychotics, which have predominantly focused on dopaminergic mechanisms.
Database: Psychology and Behavioral Sciences Collection
Description
Abstract:The article discusses the groundbreaking approval of a new antipsychotic medication, Cobenfy (xanomeline and trospium), which marks a significant shift in the treatment of schizophrenia by targeting acetylcholine instead of dopamine. This approval represents a major departure from traditional antipsychotics, which have predominantly focused on dopaminergic mechanisms.
ISSN:01612840
DOI:10.1080/01612840.2024.2427561