How Widespread is the Use of E-Cigarettes Among Adults in the United States Who Have Never Smoked? A Tale of Three Studies.

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Title: How Widespread is the Use of E-Cigarettes Among Adults in the United States Who Have Never Smoked? A Tale of Three Studies.
Authors: McKeganey, Neil (AUTHOR), Patton, Andrea (AUTHOR), Grier, Dylan (AUTHOR), Sandhu, Khushneet (AUTHOR), Barnard, Gabe (AUTHOR)
Source: Substance Use & Misuse. 2026, Vol. 61 Issue 3, p345-356. 12p.
Subjects: Cross-sectional method, Pearson correlation (Statistics), Research funding, Data analysis, Electronic cigarettes, Smoking, Fisher exact test, Descriptive statistics, Chi-squared test, Age distribution, Longitudinal method, Non-smokers, Statistics, Confidence intervals, Data analysis software, Adults
Geographic Terms: United States
Abstract: Background: Whilst e-cigarettes are a less harmful means of consuming nicotine than combustible cigarettes, concerns have been expressed about their use by adults who have never smoked (ANS). It is important to quantify the prevalence of e-cigarette use and to understand patterns of use among ANS to effectively guide public health policy and regulatory decisions. Methods: The prevalence and patterns of e-cigarette use among ANS were estimated drawing upon data from three national studies in the United States; Population Assessment of Tobacco and Health Study (n = 29,780); the Tobacco Product Prevalence Study (n = 6,428); and the National Health Interview Survey (n = 27,651). Results: An estimated 5.0 million (5.5%) to 18.6 million (11.1%) ANS have tried e-cigarettes and most of this use is experimental. An estimated 1.5 million (1.6%) to 4.8 million (2.9%) ANS currently use e-cigarettes, and current use is primarily infrequent. However, an estimated 0.5 million (0.5%) to 2.2 million (1.3%) ANS use e-cigarettes frequently. Prevalence of e-cigarette use is highest among younger (18–24 years) ANS. Conclusions: E-cigarettes are intended to be used by adults who are currently smoking combustible cigarettes as a means of quitting combustible cigarette use or substantially reducing the number of cigarettes smoked. Therefore ANS are an unintended user population. The public health impact associated with e-cigarette use by ANS depends on whether these adults are using e-cigarettes to displace combustible cigarette use (harm avoidance) or whether they would otherwise not have initiated nicotine use if e-cigarettes were not available (harm exposure). [ABSTRACT FROM AUTHOR]
Copyright of Substance Use & Misuse is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: How Widespread is the Use of E-Cigarettes Among Adults in the United States Who Have Never Smoked? A Tale of Three Studies.
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  Data: <searchLink fieldCode="AR" term="%22McKeganey%2C+Neil%22">McKeganey, Neil</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Patton%2C+Andrea%22">Patton, Andrea</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Grier%2C+Dylan%22">Grier, Dylan</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Sandhu%2C+Khushneet%22">Sandhu, Khushneet</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Barnard%2C+Gabe%22">Barnard, Gabe</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Substance+Use+%26+Misuse%22">Substance Use & Misuse</searchLink>. 2026, Vol. 61 Issue 3, p345-356. 12p.
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  Data: Background: Whilst e-cigarettes are a less harmful means of consuming nicotine than combustible cigarettes, concerns have been expressed about their use by adults who have never smoked (ANS). It is important to quantify the prevalence of e-cigarette use and to understand patterns of use among ANS to effectively guide public health policy and regulatory decisions. Methods: The prevalence and patterns of e-cigarette use among ANS were estimated drawing upon data from three national studies in the United States; Population Assessment of Tobacco and Health Study (n = 29,780); the Tobacco Product Prevalence Study (n = 6,428); and the National Health Interview Survey (n = 27,651). Results: An estimated 5.0 million (5.5%) to 18.6 million (11.1%) ANS have tried e-cigarettes and most of this use is experimental. An estimated 1.5 million (1.6%) to 4.8 million (2.9%) ANS currently use e-cigarettes, and current use is primarily infrequent. However, an estimated 0.5 million (0.5%) to 2.2 million (1.3%) ANS use e-cigarettes frequently. Prevalence of e-cigarette use is highest among younger (18–24 years) ANS. Conclusions: E-cigarettes are intended to be used by adults who are currently smoking combustible cigarettes as a means of quitting combustible cigarette use or substantially reducing the number of cigarettes smoked. Therefore ANS are an unintended user population. The public health impact associated with e-cigarette use by ANS depends on whether these adults are using e-cigarettes to displace combustible cigarette use (harm avoidance) or whether they would otherwise not have initiated nicotine use if e-cigarettes were not available (harm exposure). [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Substance Use & Misuse is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1080/10826084.2025.2560668
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 12
        StartPage: 345
    Subjects:
      – SubjectFull: Cross-sectional method
        Type: general
      – SubjectFull: Pearson correlation (Statistics)
        Type: general
      – SubjectFull: Research funding
        Type: general
      – SubjectFull: Data analysis
        Type: general
      – SubjectFull: Electronic cigarettes
        Type: general
      – SubjectFull: Smoking
        Type: general
      – SubjectFull: Fisher exact test
        Type: general
      – SubjectFull: Descriptive statistics
        Type: general
      – SubjectFull: Chi-squared test
        Type: general
      – SubjectFull: Age distribution
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      – SubjectFull: Longitudinal method
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      – SubjectFull: Non-smokers
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      – SubjectFull: Statistics
        Type: general
      – SubjectFull: Confidence intervals
        Type: general
      – SubjectFull: Data analysis software
        Type: general
      – SubjectFull: Adults
        Type: general
      – SubjectFull: United States
        Type: general
    Titles:
      – TitleFull: How Widespread is the Use of E-Cigarettes Among Adults in the United States Who Have Never Smoked? A Tale of Three Studies.
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            NameFull: McKeganey, Neil
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            NameFull: Patton, Andrea
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            NameFull: Grier, Dylan
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            NameFull: Sandhu, Khushneet
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            – D: 01
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              Text: 2026
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              Y: 2026
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            – TitleFull: Substance Use & Misuse
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