The Central Role of Oxidative Stress in the Pathogenesis of Obstructive Sleep Apnea Syndrome: Mechanisms, Biomarkers, and Clinical Implications.
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| Title: | The Central Role of Oxidative Stress in the Pathogenesis of Obstructive Sleep Apnea Syndrome: Mechanisms, Biomarkers, and Clinical Implications. |
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| Authors: | Öztürk, Mustafa Murat (AUTHOR) |
| Source: | Journal of Turkish Sleep Medicine / Türk Uyku Tıbbı Dergisi. Jun2026, Vol. 13 Issue 2, p1-9. 9p. |
| Subjects: | Sleep apnea syndrome treatment, Risk assessment, Superoxide dismutase, Metabolic disorders, Mitochondria, Adenosine triphosphate, Oxidative stress, Respiratory obstructions, Cardiovascular diseases risk factors, Reactive oxygen species, Reactive nitrogen species, Neurological disorders, Sleep apnea syndromes, Inflammation, Biomarkers, Hypoxemia, Disease risk factors, Disease complications |
| Abstract: | Obstructive sleep apnea (OSA) syndrome is an increasingly prevalent sleep disorder characterized by recurrent upper airway obstructions and associated intermittent episodes of hypoxia. OSA is associated with cardiovascular, metabolic, and neurological morbidity. Recent evidence indicates that the oxidative stress and inflammation caused by intermittent hypoxia play a central role in the pathophysiological consequences of OSA. This review aims to summarize the mechanistic links between OSA and oxidative stress, biomarkers, clinical implications, and treatment approaches. Future research directions are also discussed in light of emerging data from human and animal studies. [ABSTRACT FROM AUTHOR] |
| Copyright of Journal of Turkish Sleep Medicine / Türk Uyku Tıbbı Dergisi is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
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| Abstract: | Obstructive sleep apnea (OSA) syndrome is an increasingly prevalent sleep disorder characterized by recurrent upper airway obstructions and associated intermittent episodes of hypoxia. OSA is associated with cardiovascular, metabolic, and neurological morbidity. Recent evidence indicates that the oxidative stress and inflammation caused by intermittent hypoxia play a central role in the pathophysiological consequences of OSA. This review aims to summarize the mechanistic links between OSA and oxidative stress, biomarkers, clinical implications, and treatment approaches. Future research directions are also discussed in light of emerging data from human and animal studies. [ABSTRACT FROM AUTHOR] |
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| ISSN: | 21481504 |
| DOI: | 10.4274/jtsm.galenos.2026.25349 |
