View in EDS PDF Full Text

Stress and addiction: glucocorticoid receptor in dopaminoceptive neurons facilitates cocaine seeking.

Saved in:
Bibliographic Details
Title: Stress and addiction: glucocorticoid receptor in dopaminoceptive neurons facilitates cocaine seeking.
Authors: Ambroggi, Frédéric, Turiault, Marc, Milet, Aude, Deroche-Gamonet, Véronique, Parnaudeau, Sébastien, Balado, Eric, Barik, Jacques, van der Veen, Rixt, Maroteaux, Grégoire, Lemberger, Thomas, Schütz, Günther, Lazar, Monique, Marinelli, Michela, Piazza, Pier Vincenzo, Tronche, François
Source: Nature Neuroscience. Mar2009, Vol. 12 Issue 3, p247-249. 3p. 1 Color Photograph, 2 Graphs.
Subjects: Psychological stress, Glucocorticoid receptors, Neurons, Neurotransmitter receptors, Dopamine receptors
Abstract: The glucocorticoid receptor is a ubiquitous transcription factor mediating adaptation to environmental challenges and stress. Selective Nr3c1 (the glucocorticoid receptor gene) ablation in mouse dopaminoceptive neurons expressing dopamine receptor 1a, but not in dopamine-releasing neurons, markedly decreased the motivation of mice to self-administer cocaine, dopamine cell firing and the control exerted by dopaminoceptive neurons on dopamine cell firing activity. In contrast, anxiety was unaffected, indicating that glucocorticoid receptors modify a number of behavioral disorders through different neuronal populations. [ABSTRACT FROM AUTHOR]
Copyright of Nature Neuroscience is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
FullText Links:
  – Type: pdflink
Text:
  Availability: 0
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 36623021
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Stress and addiction: glucocorticoid receptor in dopaminoceptive neurons facilitates cocaine seeking.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Ambroggi%2C+Frédéric%22">Ambroggi, Frédéric</searchLink><br /><searchLink fieldCode="AR" term="%22Turiault%2C+Marc%22">Turiault, Marc</searchLink><br /><searchLink fieldCode="AR" term="%22Milet%2C+Aude%22">Milet, Aude</searchLink><br /><searchLink fieldCode="AR" term="%22Deroche-Gamonet%2C+Véronique%22">Deroche-Gamonet, Véronique</searchLink><br /><searchLink fieldCode="AR" term="%22Parnaudeau%2C+Sébastien%22">Parnaudeau, Sébastien</searchLink><br /><searchLink fieldCode="AR" term="%22Balado%2C+Eric%22">Balado, Eric</searchLink><br /><searchLink fieldCode="AR" term="%22Barik%2C+Jacques%22">Barik, Jacques</searchLink><br /><searchLink fieldCode="AR" term="%22van+der+Veen%2C+Rixt%22">van der Veen, Rixt</searchLink><br /><searchLink fieldCode="AR" term="%22Maroteaux%2C+Grégoire%22">Maroteaux, Grégoire</searchLink><br /><searchLink fieldCode="AR" term="%22Lemberger%2C+Thomas%22">Lemberger, Thomas</searchLink><br /><searchLink fieldCode="AR" term="%22Schütz%2C+Günther%22">Schütz, Günther</searchLink><br /><searchLink fieldCode="AR" term="%22Lazar%2C+Monique%22">Lazar, Monique</searchLink><br /><searchLink fieldCode="AR" term="%22Marinelli%2C+Michela%22">Marinelli, Michela</searchLink><br /><searchLink fieldCode="AR" term="%22Piazza%2C+Pier+Vincenzo%22">Piazza, Pier Vincenzo</searchLink><br /><searchLink fieldCode="AR" term="%22Tronche%2C+François%22">Tronche, François</searchLink>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Nature+Neuroscience%22">Nature Neuroscience</searchLink>. Mar2009, Vol. 12 Issue 3, p247-249. 3p. 1 Color Photograph, 2 Graphs.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Psychological+stress%22">Psychological stress</searchLink><br /><searchLink fieldCode="DE" term="%22Glucocorticoid+receptors%22">Glucocorticoid receptors</searchLink><br /><searchLink fieldCode="DE" term="%22Neurons%22">Neurons</searchLink><br /><searchLink fieldCode="DE" term="%22Neurotransmitter+receptors%22">Neurotransmitter receptors</searchLink><br /><searchLink fieldCode="DE" term="%22Dopamine+receptors%22">Dopamine receptors</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: The glucocorticoid receptor is a ubiquitous transcription factor mediating adaptation to environmental challenges and stress. Selective Nr3c1 (the glucocorticoid receptor gene) ablation in mouse dopaminoceptive neurons expressing dopamine receptor 1a, but not in dopamine-releasing neurons, markedly decreased the motivation of mice to self-administer cocaine, dopamine cell firing and the control exerted by dopaminoceptive neurons on dopamine cell firing activity. In contrast, anxiety was unaffected, indicating that glucocorticoid receptors modify a number of behavioral disorders through different neuronal populations. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Nature Neuroscience is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=36623021
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/nn.2282
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 3
        StartPage: 247
    Subjects:
      – SubjectFull: Psychological stress
        Type: general
      – SubjectFull: Glucocorticoid receptors
        Type: general
      – SubjectFull: Neurons
        Type: general
      – SubjectFull: Neurotransmitter receptors
        Type: general
      – SubjectFull: Dopamine receptors
        Type: general
    Titles:
      – TitleFull: Stress and addiction: glucocorticoid receptor in dopaminoceptive neurons facilitates cocaine seeking.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Ambroggi, Frédéric
      – PersonEntity:
          Name:
            NameFull: Turiault, Marc
      – PersonEntity:
          Name:
            NameFull: Milet, Aude
      – PersonEntity:
          Name:
            NameFull: Deroche-Gamonet, Véronique
      – PersonEntity:
          Name:
            NameFull: Parnaudeau, Sébastien
      – PersonEntity:
          Name:
            NameFull: Balado, Eric
      – PersonEntity:
          Name:
            NameFull: Barik, Jacques
      – PersonEntity:
          Name:
            NameFull: van der Veen, Rixt
      – PersonEntity:
          Name:
            NameFull: Maroteaux, Grégoire
      – PersonEntity:
          Name:
            NameFull: Lemberger, Thomas
      – PersonEntity:
          Name:
            NameFull: Schütz, Günther
      – PersonEntity:
          Name:
            NameFull: Lazar, Monique
      – PersonEntity:
          Name:
            NameFull: Marinelli, Michela
      – PersonEntity:
          Name:
            NameFull: Piazza, Pier Vincenzo
      – PersonEntity:
          Name:
            NameFull: Tronche, François
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 03
              Text: Mar2009
              Type: published
              Y: 2009
          Identifiers:
            – Type: issn-print
              Value: 10976256
          Numbering:
            – Type: volume
              Value: 12
            – Type: issue
              Value: 3
          Titles:
            – TitleFull: Nature Neuroscience
              Type: main
ResultId 1