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Italian validation of INQoL, a quality of life questionnaire for adults with muscle diseases.

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Title: Italian validation of INQoL, a quality of life questionnaire for adults with muscle diseases.
Authors: Sansone, Valeria A., Panzeri, M., Montanari, M., Apolone, G., Gandossini, S., Rose, M. R., Politano, L., Solimene, C., Siciliano, G., Volpi, L., Angelini, C., Palmieri, A., Toscano, A., Musumeci, O., Mongini, T., Vercelli, L., Massa, R., Panico, M. B., Grandi, M., Meola, G.
Source: European Journal of Neurology. Sep2010, Vol. 17 Issue 9, p1178-1187. 10p. 8 Charts.
Subjects: Neuromuscular diseases, Quality of life, Regression analysis, Muscle strength testing
Geographic Terms: United Kingdom
Abstract: Background and purpose: A quality of life (QoL) questionnaire for neuromuscular diseases was recently constructed and validated in the United Kingdom in a sample of adult patients with a variety of muscle disorders. Preliminary results suggested it could be a more relevant and practical measure of QoL in muscle diseases than generic health measures of QoL. The purpose of our work was: (i) To validate INQoL in Italy on a larger sample of adult patients with muscle diseases (ii) to compare INQoL to SF-36. Methods: We have translated into Italian and applied language adaptations to the original UK INQoL version. We studied 1092 patients with different muscle disorders and performed (i) test–retest reliability ( n = 80); (ii) psychometric ( n = 345), known-group ( n = 1092), external criterion ( n = 70), and concurrent validity with SF-36 ( n = 183). Results: We have translated and formally validated the Italian version of INQoL confirming and extending results obtained in the United Kingdom. In addition to good results in terms of reliability, known-group and criterion validity, a comparison with the SF-36 scales showed a stronger association between INQoL total index and SF-36 physical ( r = −0.72) than mental ( r = −0.38) summary health indexes. When considering comparable domains of INQoL and SF-36 with respect to an objective measure of muscle strength assessment (MMRC), regression analysis showed a stronger correlation using INQoL rather than SF-36 scores. Conclusions: INQoL is recommended to assess QoL in muscle diseases because of its ability to capture physical limitations that are specifically relevant to the muscle condition. [ABSTRACT FROM AUTHOR]
Copyright of European Journal of Neurology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Italian validation of INQoL, a quality of life questionnaire for adults with muscle diseases.
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  Data: <searchLink fieldCode="AR" term="%22Sansone%2C+Valeria+A%2E%22">Sansone, Valeria A.</searchLink><br /><searchLink fieldCode="AR" term="%22Panzeri%2C+M%2E%22">Panzeri, M.</searchLink><br /><searchLink fieldCode="AR" term="%22Montanari%2C+M%2E%22">Montanari, M.</searchLink><br /><searchLink fieldCode="AR" term="%22Apolone%2C+G%2E%22">Apolone, G.</searchLink><br /><searchLink fieldCode="AR" term="%22Gandossini%2C+S%2E%22">Gandossini, S.</searchLink><br /><searchLink fieldCode="AR" term="%22Rose%2C+M%2E+R%2E%22">Rose, M. R.</searchLink><br /><searchLink fieldCode="AR" term="%22Politano%2C+L%2E%22">Politano, L.</searchLink><br /><searchLink fieldCode="AR" term="%22Solimene%2C+C%2E%22">Solimene, C.</searchLink><br /><searchLink fieldCode="AR" term="%22Siciliano%2C+G%2E%22">Siciliano, G.</searchLink><br /><searchLink fieldCode="AR" term="%22Volpi%2C+L%2E%22">Volpi, L.</searchLink><br /><searchLink fieldCode="AR" term="%22Angelini%2C+C%2E%22">Angelini, C.</searchLink><br /><searchLink fieldCode="AR" term="%22Palmieri%2C+A%2E%22">Palmieri, A.</searchLink><br /><searchLink fieldCode="AR" term="%22Toscano%2C+A%2E%22">Toscano, A.</searchLink><br /><searchLink fieldCode="AR" term="%22Musumeci%2C+O%2E%22">Musumeci, O.</searchLink><br /><searchLink fieldCode="AR" term="%22Mongini%2C+T%2E%22">Mongini, T.</searchLink><br /><searchLink fieldCode="AR" term="%22Vercelli%2C+L%2E%22">Vercelli, L.</searchLink><br /><searchLink fieldCode="AR" term="%22Massa%2C+R%2E%22">Massa, R.</searchLink><br /><searchLink fieldCode="AR" term="%22Panico%2C+M%2E+B%2E%22">Panico, M. B.</searchLink><br /><searchLink fieldCode="AR" term="%22Grandi%2C+M%2E%22">Grandi, M.</searchLink><br /><searchLink fieldCode="AR" term="%22Meola%2C+G%2E%22">Meola, G.</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22European+Journal+of+Neurology%22">European Journal of Neurology</searchLink>. Sep2010, Vol. 17 Issue 9, p1178-1187. 10p. 8 Charts.
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  Data: <searchLink fieldCode="DE" term="%22Neuromuscular+diseases%22">Neuromuscular diseases</searchLink><br /><searchLink fieldCode="DE" term="%22Quality+of+life%22">Quality of life</searchLink><br /><searchLink fieldCode="DE" term="%22Regression+analysis%22">Regression analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Muscle+strength+testing%22">Muscle strength testing</searchLink>
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  Data: Background and purpose: A quality of life (QoL) questionnaire for neuromuscular diseases was recently constructed and validated in the United Kingdom in a sample of adult patients with a variety of muscle disorders. Preliminary results suggested it could be a more relevant and practical measure of QoL in muscle diseases than generic health measures of QoL. The purpose of our work was: (i) To validate INQoL in Italy on a larger sample of adult patients with muscle diseases (ii) to compare INQoL to SF-36. Methods: We have translated into Italian and applied language adaptations to the original UK INQoL version. We studied 1092 patients with different muscle disorders and performed (i) test–retest reliability ( n = 80); (ii) psychometric ( n = 345), known-group ( n = 1092), external criterion ( n = 70), and concurrent validity with SF-36 ( n = 183). Results: We have translated and formally validated the Italian version of INQoL confirming and extending results obtained in the United Kingdom. In addition to good results in terms of reliability, known-group and criterion validity, a comparison with the SF-36 scales showed a stronger association between INQoL total index and SF-36 physical ( r = −0.72) than mental ( r = −0.38) summary health indexes. When considering comparable domains of INQoL and SF-36 with respect to an objective measure of muscle strength assessment (MMRC), regression analysis showed a stronger correlation using INQoL rather than SF-36 scores. Conclusions: INQoL is recommended to assess QoL in muscle diseases because of its ability to capture physical limitations that are specifically relevant to the muscle condition. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of European Journal of Neurology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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