Quality of Life Profiles and Changes in the Course of Maintenance Treatment Among 1,015 Patients With Severe Opioid Dependence.
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| Title: | Quality of Life Profiles and Changes in the Course of Maintenance Treatment Among 1,015 Patients With Severe Opioid Dependence. |
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| Authors: | Karow, A. (AUTHOR), Verthein, U. (AUTHOR), Pukrop, R. (AUTHOR), Reimer, J. (AUTHOR), Haasen, C. (AUTHOR), Krausz, M. (AUTHOR), Schäfer, I. (AUTHOR) |
| Source: | Substance Use & Misuse. Apr2011, Vol. 46 Issue 6, p705-715. 11p. 4 Charts, 1 Graph. |
| Subjects: | Quality of life, Opioid abuse, Treatment of drug addiction, Mental depression, Schizophrenia, Sociodemographic factors, Heroin, Therapeutics |
| Abstract (English): | Introduction: Studies indicate that different areas of mental, physical, social and daily life functioning need to be considered in order to improve intervention outcomes in substance user patients. The aim of the study was to assess health-related quality of life (HRQOL) in patients diagnosed with opioid dependence as compared to healthy controls and patients diagnosed with depression and schizophrenia. Methods: A total of 1,015 outpatients diagnosed with opioid dependence were investigated during 12 months of maintenance treatment. HRQOL (MSQoL), addiction (EUROP-ASI), and sociodemographic characteristics were assessed. Results: HRQOL in opioid dependence improved significantly ( p < .001), but was lower as compared to that of healthy controls and patients diagnosed with schizophrenia. HRQOL in opioid dependence comprises addiction-specific aspects, most importantly low material satisfaction, physical health, and social stability. Conclusions: HRQOL measurement provides valuable information for course and outcome in opioid dependence treatment. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): | Perfiles de calidad de vida y cambios en el curso de tratamiento de mantenimiento en 1015 pacientes con severa dependencia de opiáceos Introducción: Estudios previos indican que diferentes areas de funcionamiento mental, físico, social y de funcionamiento diario necesitan ser consideradas con el objetivo de mejorar los resultados en pacientes con abuso de sustancias. El objetivo del presente estudio fue evaluar calidad de vida relacionado con la salud (CVRS) en pacientes dependientes de opiáceos comparados con controles sanos y pacientes con depresión y esquizofrenia. Método: 1015 pacientes externos con dependencia de opiáceos fueron investigados durante 12 meses de tratamiento de mantenimiento. Se evaluó CVRS (MSQoL), severidad de la adicción (Europ-ASI) y características sociodemográficas. Resultados. CVRS en dependenia de opiaceos mejoró de manera significativa (p <.001), pero fue menor que la de los controles sanos y los pacientes con esquizofrenia. La CVRS en dependencia a opiaceos está formada por aspectos específicos de la adicción, siendo los más importantes la baja satisfacción material, la salud física y la estabilidad social. Conclusiones. La medida de la CVRS proporciona información valiosa para el curso y los resultados en la dependencia de opiáceos. [ABSTRACT FROM AUTHOR] |
| Abstract (French): | Changements des profiles de qualité de vie au cours de traitement de substitution chez 1,015 patients avec des troubles de dépendance aux opiacés Introduction: Il à été proposé que de domaines différentes de la fonctionnement mental, physique, et sociale doivent être adressés afin d'améliorer les résultats cliniques chez des patients avec des troubles addictifs. Cette étude était destinée à examiner la qualité de vie liée à la santé (QDVLS) chez des patients avec des troubles de dépendance aux opiacés, et de comparer ce groupe à la population générale, aux patients souffrant d'une schizophrénie et aux patients avec des troubles dépressifs. Méthode: 1,015 patients avec des troubles de dépendance aux opiacés étaient examinés pendant 12 mois de traitement de substitution. Les instruments administrés comprenaient le MSQoL, l'EuropASI, et les caractéristiques sociodémographiques. Résultats: La QDVLS chez les patients avec des troubles de dépendance aux opiacés augmentait significativement (p <.001) mais était plus faible que dans la population générale et chez les patients souffrant d'une schizophrénie. Des aspects de la QDVLS spécifiques aux addictions étaient observés chez les patients avec des troubles de dépendance aux opiacés, notamment un niveau plus faible de la satisfaction matérielle, de la santé physique et de la stabilité sociale. Conclusions: Les instruments de QDVLS peuvent fournir des informations utiles concernant le cours de la maladie et les résultats cliniques chez des patients avec des troubles de dépendance aux opiacés. [ABSTRACT FROM AUTHOR] |
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| Database: | Psychology and Behavioral Sciences Collection |
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| Abstract: | Introduction: Studies indicate that different areas of mental, physical, social and daily life functioning need to be considered in order to improve intervention outcomes in substance user patients. The aim of the study was to assess health-related quality of life (HRQOL) in patients diagnosed with opioid dependence as compared to healthy controls and patients diagnosed with depression and schizophrenia. Methods: A total of 1,015 outpatients diagnosed with opioid dependence were investigated during 12 months of maintenance treatment. HRQOL (MSQoL), addiction (EUROP-ASI), and sociodemographic characteristics were assessed. Results: HRQOL in opioid dependence improved significantly ( p < .001), but was lower as compared to that of healthy controls and patients diagnosed with schizophrenia. HRQOL in opioid dependence comprises addiction-specific aspects, most importantly low material satisfaction, physical health, and social stability. Conclusions: HRQOL measurement provides valuable information for course and outcome in opioid dependence treatment. [ABSTRACT FROM AUTHOR] |
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| ISSN: | 10826084 |
| DOI: | 10.3109/10826084.2010.509854 |
