Bibliographic Details
| Title: |
Long-Term Benzodiazepine Use in Patients With Major Depressive Disorder in China. |
| Authors: |
Li, You‐Hong, Xiang, Yu‐Tao, Su, Yun‐Ai, Shu, Liang, Yu, Xin, Kilbourne, Amy M., Ungvari, Gabor S., Chiu, Helen F.K., Ma, Cui, Wang, Gao‐Hua, Bai, Pei‐Shen, Liu, Xie‐He, Sun, Li‐Zhong, Shi, Jian‐Guo, Chen, Xian‐Sheng, Mei, Qi‐Yi, Li, Ke‐Qing, Si, Tian‐Mei |
| Source: |
Perspectives in Psychiatric Care. Jul2014, Vol. 50 Issue 3, p149-154. 7p. |
| Subjects: |
Mental depression, Antidepressants, Age distribution, Benzodiazepines, Chi-squared test, Confidence intervals, T-test (Statistics), Tranquilizing drugs, U-statistics, Cross-sectional method, Data analysis software, Descriptive statistics, Odds ratio |
| Geographic Terms: |
China |
| Abstract: |
Purpose There have been no data about long-term benzodiazepine ( BZD) use and its correlates in patients with major depressive disorder ( MDD) in China. This study aimed to examine the prevalence of long-term BZD use (more than three months) and its demographic and clinical correlates in Chinese patients with MDD. Design and Methods A total of 1,192 patients with MDD were examined in 10 mental health centers in China. Patients' socio-demographic and clinical characteristics and prescriptions for psychotropic drugs were recorded using a standardized form. Findings A large portion of patients (36.2%) received long-term BZD treatment. Univariate analyses revealed that long-term BZD users were older, poorer, and had more impaired occupational functioning than patients not taking BZDs. Long-term BZD users had fewer psychotic symptoms and took less antipsychotic drugs. In multivariate analyses, long-term BZD use was independently associated with older age and more severe impaired occupational functioning; long-term BZD users were less likely to receive antipsychotic medications and traditional antidepressants (tricyclic antidepressants, tetracyclic antidepressant, and monoamine oxidase inhibitors). Practice Implications Long-term BZD use was common in patients with MDD in China. A host of demographic and clinical factors were independently associated with long-term BZD use. [ABSTRACT FROM AUTHOR] |
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| Database: |
Psychology and Behavioral Sciences Collection |
