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Long-Term Benzodiazepine Use in Patients With Major Depressive Disorder in China.

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Title: Long-Term Benzodiazepine Use in Patients With Major Depressive Disorder in China.
Authors: Li, You‐Hong, Xiang, Yu‐Tao, Su, Yun‐Ai, Shu, Liang, Yu, Xin, Kilbourne, Amy M., Ungvari, Gabor S., Chiu, Helen F.K., Ma, Cui, Wang, Gao‐Hua, Bai, Pei‐Shen, Liu, Xie‐He, Sun, Li‐Zhong, Shi, Jian‐Guo, Chen, Xian‐Sheng, Mei, Qi‐Yi, Li, Ke‐Qing, Si, Tian‐Mei
Source: Perspectives in Psychiatric Care. Jul2014, Vol. 50 Issue 3, p149-154. 7p.
Subjects: Mental depression, Antidepressants, Age distribution, Benzodiazepines, Chi-squared test, Confidence intervals, T-test (Statistics), Tranquilizing drugs, U-statistics, Cross-sectional method, Data analysis software, Descriptive statistics, Odds ratio
Geographic Terms: China
Abstract: Purpose There have been no data about long-term benzodiazepine ( BZD) use and its correlates in patients with major depressive disorder ( MDD) in China. This study aimed to examine the prevalence of long-term BZD use (more than three months) and its demographic and clinical correlates in Chinese patients with MDD. Design and Methods A total of 1,192 patients with MDD were examined in 10 mental health centers in China. Patients' socio-demographic and clinical characteristics and prescriptions for psychotropic drugs were recorded using a standardized form. Findings A large portion of patients (36.2%) received long-term BZD treatment. Univariate analyses revealed that long-term BZD users were older, poorer, and had more impaired occupational functioning than patients not taking BZDs. Long-term BZD users had fewer psychotic symptoms and took less antipsychotic drugs. In multivariate analyses, long-term BZD use was independently associated with older age and more severe impaired occupational functioning; long-term BZD users were less likely to receive antipsychotic medications and traditional antidepressants (tricyclic antidepressants, tetracyclic antidepressant, and monoamine oxidase inhibitors). Practice Implications Long-term BZD use was common in patients with MDD in China. A host of demographic and clinical factors were independently associated with long-term BZD use. [ABSTRACT FROM AUTHOR]
Copyright of Perspectives in Psychiatric Care is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Long-Term Benzodiazepine Use in Patients With Major Depressive Disorder in China.
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  Data: <searchLink fieldCode="AR" term="%22Li%2C+You‐Hong%22">Li, You‐Hong</searchLink><br /><searchLink fieldCode="AR" term="%22Xiang%2C+Yu‐Tao%22">Xiang, Yu‐Tao</searchLink><br /><searchLink fieldCode="AR" term="%22Su%2C+Yun‐Ai%22">Su, Yun‐Ai</searchLink><br /><searchLink fieldCode="AR" term="%22Shu%2C+Liang%22">Shu, Liang</searchLink><br /><searchLink fieldCode="AR" term="%22Yu%2C+Xin%22">Yu, Xin</searchLink><br /><searchLink fieldCode="AR" term="%22Kilbourne%2C+Amy+M%2E%22">Kilbourne, Amy M.</searchLink><br /><searchLink fieldCode="AR" term="%22Ungvari%2C+Gabor+S%2E%22">Ungvari, Gabor S.</searchLink><br /><searchLink fieldCode="AR" term="%22Chiu%2C+Helen+F%2EK%2E%22">Chiu, Helen F.K.</searchLink><br /><searchLink fieldCode="AR" term="%22Ma%2C+Cui%22">Ma, Cui</searchLink><br /><searchLink fieldCode="AR" term="%22Wang%2C+Gao‐Hua%22">Wang, Gao‐Hua</searchLink><br /><searchLink fieldCode="AR" term="%22Bai%2C+Pei‐Shen%22">Bai, Pei‐Shen</searchLink><br /><searchLink fieldCode="AR" term="%22Liu%2C+Xie‐He%22">Liu, Xie‐He</searchLink><br /><searchLink fieldCode="AR" term="%22Sun%2C+Li‐Zhong%22">Sun, Li‐Zhong</searchLink><br /><searchLink fieldCode="AR" term="%22Shi%2C+Jian‐Guo%22">Shi, Jian‐Guo</searchLink><br /><searchLink fieldCode="AR" term="%22Chen%2C+Xian‐Sheng%22">Chen, Xian‐Sheng</searchLink><br /><searchLink fieldCode="AR" term="%22Mei%2C+Qi‐Yi%22">Mei, Qi‐Yi</searchLink><br /><searchLink fieldCode="AR" term="%22Li%2C+Ke‐Qing%22">Li, Ke‐Qing</searchLink><br /><searchLink fieldCode="AR" term="%22Si%2C+Tian‐Mei%22">Si, Tian‐Mei</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22Perspectives+in+Psychiatric+Care%22">Perspectives in Psychiatric Care</searchLink>. Jul2014, Vol. 50 Issue 3, p149-154. 7p.
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  Data: <searchLink fieldCode="DE" term="%22Mental+depression%22">Mental depression</searchLink><br /><searchLink fieldCode="DE" term="%22Antidepressants%22">Antidepressants</searchLink><br /><searchLink fieldCode="DE" term="%22Age+distribution%22">Age distribution</searchLink><br /><searchLink fieldCode="DE" term="%22Benzodiazepines%22">Benzodiazepines</searchLink><br /><searchLink fieldCode="DE" term="%22Chi-squared+test%22">Chi-squared test</searchLink><br /><searchLink fieldCode="DE" term="%22Confidence+intervals%22">Confidence intervals</searchLink><br /><searchLink fieldCode="DE" term="%22T-test+%28Statistics%29%22">T-test (Statistics)</searchLink><br /><searchLink fieldCode="DE" term="%22Tranquilizing+drugs%22">Tranquilizing drugs</searchLink><br /><searchLink fieldCode="DE" term="%22U-statistics%22">U-statistics</searchLink><br /><searchLink fieldCode="DE" term="%22Cross-sectional+method%22">Cross-sectional method</searchLink><br /><searchLink fieldCode="DE" term="%22Data+analysis+software%22">Data analysis software</searchLink><br /><searchLink fieldCode="DE" term="%22Descriptive+statistics%22">Descriptive statistics</searchLink><br /><searchLink fieldCode="DE" term="%22Odds+ratio%22">Odds ratio</searchLink>
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  Data: <searchLink fieldCode="DE" term="%22China%22">China</searchLink>
– Name: Abstract
  Label: Abstract
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  Data: Purpose There have been no data about long-term benzodiazepine ( BZD) use and its correlates in patients with major depressive disorder ( MDD) in China. This study aimed to examine the prevalence of long-term BZD use (more than three months) and its demographic and clinical correlates in Chinese patients with MDD. Design and Methods A total of 1,192 patients with MDD were examined in 10 mental health centers in China. Patients' socio-demographic and clinical characteristics and prescriptions for psychotropic drugs were recorded using a standardized form. Findings A large portion of patients (36.2%) received long-term BZD treatment. Univariate analyses revealed that long-term BZD users were older, poorer, and had more impaired occupational functioning than patients not taking BZDs. Long-term BZD users had fewer psychotic symptoms and took less antipsychotic drugs. In multivariate analyses, long-term BZD use was independently associated with older age and more severe impaired occupational functioning; long-term BZD users were less likely to receive antipsychotic medications and traditional antidepressants (tricyclic antidepressants, tetracyclic antidepressant, and monoamine oxidase inhibitors). Practice Implications Long-term BZD use was common in patients with MDD in China. A host of demographic and clinical factors were independently associated with long-term BZD use. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Perspectives in Psychiatric Care is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=96924254
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        Value: 10.1111/ppc.12035
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        Text: English
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      – SubjectFull: Antidepressants
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      – SubjectFull: Age distribution
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      – SubjectFull: Data analysis software
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      – SubjectFull: Descriptive statistics
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      – SubjectFull: Odds ratio
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      – SubjectFull: China
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