Biomimetic chitosan-derived bifunctional lubricant with superior antibacterial and hydration lubrication performances.
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| Title: | Biomimetic chitosan-derived bifunctional lubricant with superior antibacterial and hydration lubrication performances. |
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| Authors: | Yang, Lumin1,2 (AUTHOR), Zhao, Xiaoduo1,3 (AUTHOR), Liao, Xiaozhu4 (AUTHOR), Wang, Rui1,3 (AUTHOR), Fan, Zengjie4 (AUTHOR), Ma, Shuanhong1,3 (AUTHOR) mashuanhong@licp.cas.cn, Zhou, Feng1 (AUTHOR) zhouf@licp.cas.cn |
| Source: | Journal of Colloid & Interface Science. Jan2023:Part B, Vol. 629, p859-870. 12p. |
| Subjects: | Infectious arthritis, Artificial joints, Articular cartilage, Peptides, Lubrication & lubricants, Polysaccharides |
| Abstract: | Novel chitosan-derived biolubricant (CS-MPC-N) with both anti-bacterial and lubrication functions. [Display omitted] The lubrication deficiency in joints is a major cause of osteoarthritis. One of the most commonly used treatment means is to inject artificial lubricants, but there is a potential risk of infection during the injection process. Therefore, developing artificial lubricants with dual functions of friction-reduction and antibacterial is urgent. In this work, a novel polysaccharide-derived lubricant with simultaneous anti-bacteria and water-lubrication properties, called CS-MPC-N, is developed by grafting 2‑methacryloyloxylethyl phosphorylcholine (MPC) and nisin peptide onto backbone of chitosan (CS). Compared to the control CS, CS-MPC-N exhibits good lubrication and friction-reduction properties because of its excellent water solubility. Especially, CS-MPC-N shows low friction coefficient (0.03 ∼ 0.05) at the sliding interfaces of artificial joints materials or even natural articular cartilages. Moreover, CS-MPC-N can effectively inhibit the proliferation of Staphylococcus aureu, exhibiting excellent antibacterial effect. This kind of novel polysaccharide-derived lubricant is expected to be used in treating infectious arthritis. [ABSTRACT FROM AUTHOR] |
| Copyright of Journal of Colloid & Interface Science is the property of Academic Press Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Text: Availability: 0 |
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| Header | DbId: egs DbLabel: Engineering Source An: 159927070 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Biomimetic chitosan-derived bifunctional lubricant with superior antibacterial and hydration lubrication performances. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Yang%2C+Lumin%22">Yang, Lumin</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Zhao%2C+Xiaoduo%22">Zhao, Xiaoduo</searchLink><relatesTo>1,3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Liao%2C+Xiaozhu%22">Liao, Xiaozhu</searchLink><relatesTo>4</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Wang%2C+Rui%22">Wang, Rui</searchLink><relatesTo>1,3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Fan%2C+Zengjie%22">Fan, Zengjie</searchLink><relatesTo>4</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Ma%2C+Shuanhong%22">Ma, Shuanhong</searchLink><relatesTo>1,3</relatesTo> (AUTHOR)<i> mashuanhong@licp.cas.cn</i><br /><searchLink fieldCode="AR" term="%22Zhou%2C+Feng%22">Zhou, Feng</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> zhouf@licp.cas.cn</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Journal+of+Colloid+%26+Interface+Science%22">Journal of Colloid & Interface Science</searchLink>. Jan2023:Part B, Vol. 629, p859-870. 12p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Infectious+arthritis%22">Infectious arthritis</searchLink><br /><searchLink fieldCode="DE" term="%22Artificial+joints%22">Artificial joints</searchLink><br /><searchLink fieldCode="DE" term="%22Articular+cartilage%22">Articular cartilage</searchLink><br /><searchLink fieldCode="DE" term="%22Peptides%22">Peptides</searchLink><br /><searchLink fieldCode="DE" term="%22Lubrication+%26+lubricants%22">Lubrication & lubricants</searchLink><br /><searchLink fieldCode="DE" term="%22Polysaccharides%22">Polysaccharides</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Novel chitosan-derived biolubricant (CS-MPC-N) with both anti-bacterial and lubrication functions. [Display omitted] The lubrication deficiency in joints is a major cause of osteoarthritis. One of the most commonly used treatment means is to inject artificial lubricants, but there is a potential risk of infection during the injection process. Therefore, developing artificial lubricants with dual functions of friction-reduction and antibacterial is urgent. In this work, a novel polysaccharide-derived lubricant with simultaneous anti-bacteria and water-lubrication properties, called CS-MPC-N, is developed by grafting 2‑methacryloyloxylethyl phosphorylcholine (MPC) and nisin peptide onto backbone of chitosan (CS). Compared to the control CS, CS-MPC-N exhibits good lubrication and friction-reduction properties because of its excellent water solubility. Especially, CS-MPC-N shows low friction coefficient (0.03 ∼ 0.05) at the sliding interfaces of artificial joints materials or even natural articular cartilages. Moreover, CS-MPC-N can effectively inhibit the proliferation of Staphylococcus aureu, exhibiting excellent antibacterial effect. This kind of novel polysaccharide-derived lubricant is expected to be used in treating infectious arthritis. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Journal of Colloid & Interface Science is the property of Academic Press Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.jcis.2022.09.098 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 12 StartPage: 859 Subjects: – SubjectFull: Infectious arthritis Type: general – SubjectFull: Artificial joints Type: general – SubjectFull: Articular cartilage Type: general – SubjectFull: Peptides Type: general – SubjectFull: Lubrication & lubricants Type: general – SubjectFull: Polysaccharides Type: general Titles: – TitleFull: Biomimetic chitosan-derived bifunctional lubricant with superior antibacterial and hydration lubrication performances. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Yang, Lumin – PersonEntity: Name: NameFull: Zhao, Xiaoduo – PersonEntity: Name: NameFull: Liao, Xiaozhu – PersonEntity: Name: NameFull: Wang, Rui – PersonEntity: Name: NameFull: Fan, Zengjie – PersonEntity: Name: NameFull: Ma, Shuanhong – PersonEntity: Name: NameFull: Zhou, Feng IsPartOfRelationships: – BibEntity: Dates: – D: 15 M: 01 Text: Jan2023:Part B Type: published Y: 2023 Identifiers: – Type: issn-print Value: 00219797 Numbering: – Type: volume Value: 629 Titles: – TitleFull: Journal of Colloid & Interface Science Type: main |
| ResultId | 1 |