New conjugates based on N4-hydroxycytidine with more potent antiviral efficacy in vitro than EIDD-2801 against SARS-CoV-2 and other human coronaviruses.
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| Title: | New conjugates based on N4-hydroxycytidine with more potent antiviral efficacy in vitro than EIDD-2801 against SARS-CoV-2 and other human coronaviruses. |
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| Authors: | Siniavin AE; Department of Epidemiology, Federal State Budget Institution 'National Research Centre for Epidemiology and Microbiology Named After Honorary Academician N. F. Gamaleya' of the Ministry of Health of the Russian Federation, 123098, Moscow, Russia; Department of Molecular Neuroimmune Signaling, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997, Moscow, Russia. Electronic address: andreysi93@ya.ru., Gushchin VA; Department of Epidemiology, Federal State Budget Institution 'National Research Centre for Epidemiology and Microbiology Named After Honorary Academician N. F. Gamaleya' of the Ministry of Health of the Russian Federation, 123098, Moscow, Russia; Department of Medical Genetics, Federal State Autonomous Educational Institution of Higher Education I M Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 119991, Moscow, Russia; Department of Virology, Faculty of Biology Lomonosov Moscow State University, 119234, Moscow, Russia. Electronic address: wowaniada@yandex.ru., Shastina NS; Department of Epidemiology, Federal State Budget Institution 'National Research Centre for Epidemiology and Microbiology Named After Honorary Academician N. F. Gamaleya' of the Ministry of Health of the Russian Federation, 123098, Moscow, Russia; Institute of Fine Chemical Technologies, MIREA-Russian Technological University, 119571, Moscow, Russia., Darnotuk ES; Department of Epidemiology, Federal State Budget Institution 'National Research Centre for Epidemiology and Microbiology Named After Honorary Academician N. F. Gamaleya' of the Ministry of Health of the Russian Federation, 123098, Moscow, Russia; Institute of Fine Chemical Technologies, MIREA-Russian Technological University, 119571, Moscow, Russia., Luyksaar SI; Department of Epidemiology, Federal State Budget Institution 'National Research Centre for Epidemiology and Microbiology Named After Honorary Academician N. F. Gamaleya' of the Ministry of Health of the Russian Federation, 123098, Moscow, Russia., Russu LI; Department of Epidemiology, Federal State Budget Institution 'National Research Centre for Epidemiology and Microbiology Named After Honorary Academician N. F. Gamaleya' of the Ministry of Health of the Russian Federation, 123098, Moscow, Russia., Inshakova AM; Department of Epidemiology, Federal State Budget Institution 'National Research Centre for Epidemiology and Microbiology Named After Honorary Academician N. F. Gamaleya' of the Ministry of Health of the Russian Federation, 123098, Moscow, Russia; Institute of Fine Chemical Technologies, MIREA-Russian Technological University, 119571, Moscow, Russia., Shidlovskaya EV; Department of Epidemiology, Federal State Budget Institution 'National Research Centre for Epidemiology and Microbiology Named After Honorary Academician N. F. Gamaleya' of the Ministry of Health of the Russian Federation, 123098, Moscow, Russia., Vasina DV; Department of Epidemiology, Federal State Budget Institution 'National Research Centre for Epidemiology and Microbiology Named After Honorary Academician N. F. Gamaleya' of the Ministry of Health of the Russian Federation, 123098, Moscow, Russia., Kuznetsova NA; Department of Epidemiology, Federal State Budget Institution 'National Research Centre for Epidemiology and Microbiology Named After Honorary Academician N. F. Gamaleya' of the Ministry of Health of the Russian Federation, 123098, Moscow, Russia., Savina DM; Department of Epidemiology, Federal State Budget Institution 'National Research Centre for Epidemiology and Microbiology Named After Honorary Academician N. F. Gamaleya' of the Ministry of Health of the Russian Federation, 123098, Moscow, Russia., Zorkov ID; Department of Epidemiology, Federal State Budget Institution 'National Research Centre for Epidemiology and Microbiology Named After Honorary Academician N. F. Gamaleya' of the Ministry of Health of the Russian Federation, 123098, Moscow, Russia., Dolzhikova IV; Department of Epidemiology, Federal State Budget Institution 'National Research Centre for Epidemiology and Microbiology Named After Honorary Academician N. F. Gamaleya' of the Ministry of Health of the Russian Federation, 123098, Moscow, Russia., Sheremet AB; Department of Epidemiology, Federal State Budget Institution 'National Research Centre for Epidemiology and Microbiology Named After Honorary Academician N. F. Gamaleya' of the Ministry of Health of the Russian Federation, 123098, Moscow, Russia., Logunov DY; Department of Epidemiology, Federal State Budget Institution 'National Research Centre for Epidemiology and Microbiology Named After Honorary Academician N. F. Gamaleya' of the Ministry of Health of the Russian Federation, 123098, Moscow, Russia., Zigangirova NA; Department of Epidemiology, Federal State Budget Institution 'National Research Centre for Epidemiology and Microbiology Named After Honorary Academician N. F. Gamaleya' of the Ministry of Health of the Russian Federation, 123098, Moscow, Russia., Gintsburg AL; Department of Epidemiology, Federal State Budget Institution 'National Research Centre for Epidemiology and Microbiology Named After Honorary Academician N. F. Gamaleya' of the Ministry of Health of the Russian Federation, 123098, Moscow, Russia; Department of Infectology and Virology, Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov, First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 119435, Moscow, Russia. |
| Source: | Antiviral research [Antiviral Res] 2024 May; Vol. 225, pp. 105871. Date of Electronic Publication: 2024 Mar 28. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8109699 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9096 (Electronic) Linking ISSN: 01663542 NLM ISO Abbreviation: Antiviral Res Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 38555022 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: New conjugates based on N4-hydroxycytidine with more potent antiviral efficacy in vitro than EIDD-2801 against SARS-CoV-2 and other human coronaviruses. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Siniavin+AE%22">Siniavin AE</searchLink>; Department of Epidemiology, Federal State Budget Institution 'National Research Centre for Epidemiology and Microbiology Named After Honorary Academician N. F. Gamaleya' of the Ministry of Health of the Russian Federation, 123098, Moscow, Russia; Department of Molecular Neuroimmune Signaling, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997, Moscow, Russia. Electronic address: andreysi93@ya.ru.<br /><searchLink fieldCode="AU" term="%22Gushchin+VA%22">Gushchin VA</searchLink>; Department of Epidemiology, Federal State Budget Institution 'National Research Centre for Epidemiology and Microbiology Named After Honorary Academician N. F. Gamaleya' of the Ministry of Health of the Russian Federation, 123098, Moscow, Russia; Department of Medical Genetics, Federal State Autonomous Educational Institution of Higher Education I M Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 119991, Moscow, Russia; Department of Virology, Faculty of Biology Lomonosov Moscow State University, 119234, Moscow, Russia. Electronic address: wowaniada@yandex.ru.<br /><searchLink fieldCode="AU" term="%22Shastina+NS%22">Shastina NS</searchLink>; Department of Epidemiology, Federal State Budget Institution 'National Research Centre for Epidemiology and Microbiology Named After Honorary Academician N. F. Gamaleya' of the Ministry of Health of the Russian Federation, 123098, Moscow, Russia; Institute of Fine Chemical Technologies, MIREA-Russian Technological University, 119571, Moscow, Russia.<br /><searchLink fieldCode="AU" term="%22Darnotuk+ES%22">Darnotuk ES</searchLink>; Department of Epidemiology, Federal State Budget Institution 'National Research Centre for Epidemiology and Microbiology Named After Honorary Academician N. F. Gamaleya' of the Ministry of Health of the Russian Federation, 123098, Moscow, Russia; Institute of Fine Chemical Technologies, MIREA-Russian Technological University, 119571, Moscow, Russia.<br /><searchLink fieldCode="AU" term="%22Luyksaar+SI%22">Luyksaar SI</searchLink>; Department of Epidemiology, Federal State Budget Institution 'National Research Centre for Epidemiology and Microbiology Named After Honorary Academician N. F. Gamaleya' of the Ministry of Health of the Russian Federation, 123098, Moscow, Russia.<br /><searchLink fieldCode="AU" term="%22Russu+LI%22">Russu LI</searchLink>; Department of Epidemiology, Federal State Budget Institution 'National Research Centre for Epidemiology and Microbiology Named After Honorary Academician N. F. Gamaleya' of the Ministry of Health of the Russian Federation, 123098, Moscow, Russia.<br /><searchLink fieldCode="AU" term="%22Inshakova+AM%22">Inshakova AM</searchLink>; Department of Epidemiology, Federal State Budget Institution 'National Research Centre for Epidemiology and Microbiology Named After Honorary Academician N. F. Gamaleya' of the Ministry of Health of the Russian Federation, 123098, Moscow, Russia; Institute of Fine Chemical Technologies, MIREA-Russian Technological University, 119571, Moscow, Russia.<br /><searchLink fieldCode="AU" term="%22Shidlovskaya+EV%22">Shidlovskaya EV</searchLink>; Department of Epidemiology, Federal State Budget Institution 'National Research Centre for Epidemiology and Microbiology Named After Honorary Academician N. F. Gamaleya' of the Ministry of Health of the Russian Federation, 123098, Moscow, Russia.<br /><searchLink fieldCode="AU" term="%22Vasina+DV%22">Vasina DV</searchLink>; Department of Epidemiology, Federal State Budget Institution 'National Research Centre for Epidemiology and Microbiology Named After Honorary Academician N. F. Gamaleya' of the Ministry of Health of the Russian Federation, 123098, Moscow, Russia.<br /><searchLink fieldCode="AU" term="%22Kuznetsova+NA%22">Kuznetsova NA</searchLink>; Department of Epidemiology, Federal State Budget Institution 'National Research Centre for Epidemiology and Microbiology Named After Honorary Academician N. F. Gamaleya' of the Ministry of Health of the Russian Federation, 123098, Moscow, Russia.<br /><searchLink fieldCode="AU" term="%22Savina+DM%22">Savina DM</searchLink>; Department of Epidemiology, Federal State Budget Institution 'National Research Centre for Epidemiology and Microbiology Named After Honorary Academician N. F. Gamaleya' of the Ministry of Health of the Russian Federation, 123098, Moscow, Russia.<br /><searchLink fieldCode="AU" term="%22Zorkov+ID%22">Zorkov ID</searchLink>; Department of Epidemiology, Federal State Budget Institution 'National Research Centre for Epidemiology and Microbiology Named After Honorary Academician N. F. Gamaleya' of the Ministry of Health of the Russian Federation, 123098, Moscow, Russia.<br /><searchLink fieldCode="AU" term="%22Dolzhikova+IV%22">Dolzhikova IV</searchLink>; Department of Epidemiology, Federal State Budget Institution 'National Research Centre for Epidemiology and Microbiology Named After Honorary Academician N. F. Gamaleya' of the Ministry of Health of the Russian Federation, 123098, Moscow, Russia.<br /><searchLink fieldCode="AU" term="%22Sheremet+AB%22">Sheremet AB</searchLink>; Department of Epidemiology, Federal State Budget Institution 'National Research Centre for Epidemiology and Microbiology Named After Honorary Academician N. F. Gamaleya' of the Ministry of Health of the Russian Federation, 123098, Moscow, Russia.<br /><searchLink fieldCode="AU" term="%22Logunov+DY%22">Logunov DY</searchLink>; Department of Epidemiology, Federal State Budget Institution 'National Research Centre for Epidemiology and Microbiology Named After Honorary Academician N. F. Gamaleya' of the Ministry of Health of the Russian Federation, 123098, Moscow, Russia.<br /><searchLink fieldCode="AU" term="%22Zigangirova+NA%22">Zigangirova NA</searchLink>; Department of Epidemiology, Federal State Budget Institution 'National Research Centre for Epidemiology and Microbiology Named After Honorary Academician N. F. Gamaleya' of the Ministry of Health of the Russian Federation, 123098, Moscow, Russia.<br /><searchLink fieldCode="AU" term="%22Gintsburg+AL%22">Gintsburg AL</searchLink>; Department of Epidemiology, Federal State Budget Institution 'National Research Centre for Epidemiology and Microbiology Named After Honorary Academician N. F. Gamaleya' of the Ministry of Health of the Russian Federation, 123098, Moscow, Russia; Department of Infectology and Virology, Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov, First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 119435, Moscow, Russia. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%228109699%22">Antiviral research</searchLink> [Antiviral Res] 2024 May; Vol. 225, pp. 105871. <i>Date of Electronic Publication: </i>2024 Mar 28. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>8109699 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1872-9096 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201663542%22">01663542 </searchLink><i>NLM ISO Abbreviation: </i>Antiviral Res <i>Subsets: </i>MEDLINE |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.antiviral.2024.105871 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 105871 Titles: – TitleFull: New conjugates based on N4-hydroxycytidine with more potent antiviral efficacy in vitro than EIDD-2801 against SARS-CoV-2 and other human coronaviruses. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Siniavin AE – PersonEntity: Name: NameFull: Gushchin VA – PersonEntity: Name: NameFull: Shastina NS – PersonEntity: Name: NameFull: Darnotuk ES – PersonEntity: Name: NameFull: Luyksaar SI – PersonEntity: Name: NameFull: Russu LI – PersonEntity: Name: NameFull: Inshakova AM – PersonEntity: Name: NameFull: Shidlovskaya EV – PersonEntity: Name: NameFull: Vasina DV – PersonEntity: Name: NameFull: Kuznetsova NA – PersonEntity: Name: NameFull: Savina DM – PersonEntity: Name: NameFull: Zorkov ID – PersonEntity: Name: NameFull: Dolzhikova IV – PersonEntity: Name: NameFull: Sheremet AB – PersonEntity: Name: NameFull: Logunov DY – PersonEntity: Name: NameFull: Zigangirova NA – PersonEntity: Name: NameFull: Gintsburg AL IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 05 Text: 2024 May Type: published Y: 2024 Identifiers: – Type: issn-electronic Value: 1872-9096 Numbering: – Type: volume Value: 225 Titles: – TitleFull: Antiviral research Type: main |
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