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CRISPR/Cas9-mediated deletion of MADD induces cell cycle arrest and apoptosis in anaplastic thyroid cancer cells.

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Title: CRISPR/Cas9-mediated deletion of MADD induces cell cycle arrest and apoptosis in anaplastic thyroid cancer cells.
Authors: Bakthavachalam V; Department of Microbiology and Immunology, University of Illinois College of Medicine, Chicago, IL, 60612, USA., Sanborn MA; Department of Biochemistry and Molecular Genetics, University of Illinois College of Medicine, Chicago, IL, 60607, USA., Mathayan M; Department of Microbiology and Immunology, University of Illinois College of Medicine, Chicago, IL, 60612, USA., Salunkhe SS; Department of Microbiology and Immunology, University of Illinois College of Medicine, Chicago, IL, 60612, USA., Wood JM; Research Informatics Core, University of Illinois at Chicago, Chicago, IL, 60612, USA., Maienschein-Cline M; Research Informatics Core, University of Illinois at Chicago, Chicago, IL, 60612, USA., Setty S; Department of Pathology, University of Illinois College of Medicine, Chicago, IL, 60612, USA., Kabeer BSA; Center for Global Health Research, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, India., Rehman J; Department of Biochemistry and Molecular Genetics, University of Illinois College of Medicine, Chicago, IL, 60607, USA.; University of Illinois Cancer Center, Chicago, IL, 60612, USA., Prabhakar BS; Scientist Jesse Brown VA Medical Center, Chicago, IL, 60612, USA. bprabhak@uic.edu.; University of Illinois Cancer Center, Chicago, IL, 60612, USA. bprabhak@uic.edu.; Department of Microbiology and Immunology, University of Illinois College of Medicine, Chicago, IL, 60612, USA. bprabhak@uic.edu.
Source: Scientific reports [Sci Rep] 2025 Nov 10; Vol. 15 (1), pp. 39264. Date of Electronic Publication: 2025 Nov 10.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: CRISPR/Cas9-mediated deletion of MADD induces cell cycle arrest and apoptosis in anaplastic thyroid cancer cells.
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  Data: <searchLink fieldCode="AU" term="%22Bakthavachalam+V%22">Bakthavachalam V</searchLink>; Department of Microbiology and Immunology, University of Illinois College of Medicine, Chicago, IL, 60612, USA.<br /><searchLink fieldCode="AU" term="%22Sanborn+MA%22">Sanborn MA</searchLink>; Department of Biochemistry and Molecular Genetics, University of Illinois College of Medicine, Chicago, IL, 60607, USA.<br /><searchLink fieldCode="AU" term="%22Mathayan+M%22">Mathayan M</searchLink>; Department of Microbiology and Immunology, University of Illinois College of Medicine, Chicago, IL, 60612, USA.<br /><searchLink fieldCode="AU" term="%22Salunkhe+SS%22">Salunkhe SS</searchLink>; Department of Microbiology and Immunology, University of Illinois College of Medicine, Chicago, IL, 60612, USA.<br /><searchLink fieldCode="AU" term="%22Wood+JM%22">Wood JM</searchLink>; Research Informatics Core, University of Illinois at Chicago, Chicago, IL, 60612, USA.<br /><searchLink fieldCode="AU" term="%22Maienschein-Cline+M%22">Maienschein-Cline M</searchLink>; Research Informatics Core, University of Illinois at Chicago, Chicago, IL, 60612, USA.<br /><searchLink fieldCode="AU" term="%22Setty+S%22">Setty S</searchLink>; Department of Pathology, University of Illinois College of Medicine, Chicago, IL, 60612, USA.<br /><searchLink fieldCode="AU" term="%22Kabeer+BSA%22">Kabeer BSA</searchLink>; Center for Global Health Research, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, India.<br /><searchLink fieldCode="AU" term="%22Rehman+J%22">Rehman J</searchLink>; Department of Biochemistry and Molecular Genetics, University of Illinois College of Medicine, Chicago, IL, 60607, USA.; University of Illinois Cancer Center, Chicago, IL, 60612, USA.<br /><searchLink fieldCode="AU" term="%22Prabhakar+BS%22">Prabhakar BS</searchLink>; Scientist Jesse Brown VA Medical Center, Chicago, IL, 60612, USA. bprabhak@uic.edu.; University of Illinois Cancer Center, Chicago, IL, 60612, USA. bprabhak@uic.edu.; Department of Microbiology and Immunology, University of Illinois College of Medicine, Chicago, IL, 60612, USA. bprabhak@uic.edu.
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  Data: <searchLink fieldCode="JN" term="%22101563288%22">Scientific reports</searchLink> [Sci Rep] 2025 Nov 10; Vol. 15 (1), pp. 39264. <i>Date of Electronic Publication: </i>2025 Nov 10.
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              Text: 2025 Nov 10
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