PD-L1 expression combined with immune phenotype is a potential predictor of outcome with PD-1 inhibitor monotherapy in patients with recurrent or metastatic head and neck squamous cell carcinoma.

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Title: PD-L1 expression combined with immune phenotype is a potential predictor of outcome with PD-1 inhibitor monotherapy in patients with recurrent or metastatic head and neck squamous cell carcinoma.
Authors: Kim DH; Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea; Department of Translational Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea., Koh J; Department of Pathology, Seoul National University Hospital, Seoul, Republic of Korea; Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea., Ahn JS; Lunit Inc, Seoul, Republic of Korea., Moon J; Lunit Inc, Seoul, Republic of Korea., Kang M; Lunit Inc, Seoul, Republic of Korea., Park G; Lunit Inc, Seoul, Republic of Korea., Lim Y; Lunit Inc, Seoul, Republic of Korea., Ock CY; Lunit Inc, Seoul, Republic of Korea., Jeon YK; Department of Pathology, Seoul National University Hospital, Seoul, Republic of Korea; Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea., Jung KC; Department of Pathology, Seoul National University Hospital, Seoul, Republic of Korea., Ahn SH; Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul, Republic of Korea., Chung EJ; Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul, Republic of Korea., Kwon SK; Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul, Republic of Korea., Keam B; Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea; Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea. Electronic address: bhumsuk@snu.ac.kr.
Source: Oral surgery, oral medicine, oral pathology and oral radiology [Oral Surg Oral Med Oral Pathol Oral Radiol] 2026 May; Vol. 141 (5), pp. 679-689. Date of Electronic Publication: 2025 Dec 09.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101576782 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2212-4411 (Electronic) NLM ISO Abbreviation: Oral Surg Oral Med Oral Pathol Oral Radiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: PD-L1 expression combined with immune phenotype is a potential predictor of outcome with PD-1 inhibitor monotherapy in patients with recurrent or metastatic head and neck squamous cell carcinoma.
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  Data: <searchLink fieldCode="AU" term="%22Kim+DH%22">Kim DH</searchLink>; Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea; Department of Translational Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Koh+J%22">Koh J</searchLink>; Department of Pathology, Seoul National University Hospital, Seoul, Republic of Korea; Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Ahn+JS%22">Ahn JS</searchLink>; Lunit Inc, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Moon+J%22">Moon J</searchLink>; Lunit Inc, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kang+M%22">Kang M</searchLink>; Lunit Inc, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+G%22">Park G</searchLink>; Lunit Inc, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lim+Y%22">Lim Y</searchLink>; Lunit Inc, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Ock+CY%22">Ock CY</searchLink>; Lunit Inc, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jeon+YK%22">Jeon YK</searchLink>; Department of Pathology, Seoul National University Hospital, Seoul, Republic of Korea; Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jung+KC%22">Jung KC</searchLink>; Department of Pathology, Seoul National University Hospital, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Ahn+SH%22">Ahn SH</searchLink>; Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Chung+EJ%22">Chung EJ</searchLink>; Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kwon+SK%22">Kwon SK</searchLink>; Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Keam+B%22">Keam B</searchLink>; Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea; Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea. Electronic address: bhumsuk@snu.ac.kr.
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  Data: <searchLink fieldCode="JN" term="%22101576782%22">Oral surgery, oral medicine, oral pathology and oral radiology</searchLink> [Oral Surg Oral Med Oral Pathol Oral Radiol] 2026 May; Vol. 141 (5), pp. 679-689. <i>Date of Electronic Publication: </i>2025 Dec 09.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101576782 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2212-4411 (Electronic) <i>NLM ISO Abbreviation: </i>Oral Surg Oral Med Oral Pathol Oral Radiol <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.oooo.2025.11.018
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              Text: 2026 May
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