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Antimicrobial peptide-induced inner membrane hyperpolarization is associated with antibiotic sensitization and attenuated MIC escalation in multidrug-resistant Gram-negative pathogens.

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Title: Antimicrobial peptide-induced inner membrane hyperpolarization is associated with antibiotic sensitization and attenuated MIC escalation in multidrug-resistant Gram-negative pathogens.
Authors: Yeh JC; Marine Research Station, Institute of Cellular and Organismic Biology, Academia Sinica, Jiaushi, Ilan, Taiwan, ROC., Hazam PK; Marine Research Station, Institute of Cellular and Organismic Biology, Academia Sinica, Jiaushi, Ilan, Taiwan, ROC.; Faculty of Pharmaceutical Science, Assam down town University, Guwahati, Assam, India., Lin YY; Marine Research Station, Institute of Cellular and Organismic Biology, Academia Sinica, Jiaushi, Ilan, Taiwan, ROC., Chang YC; Academia Sinica Cryo-EM Center, Academia Sinica, Taipei, Taiwan, ROC., Selvaraj SP; Molecular and Biological Agricultural Science Program, Taiwan International Graduate Program, Academia Sinica, Taipei, Taiwan, ROC.; Graduate Institute of Biotechnology, National Chung Hsing University, Taichung, Taiwan, ROC., Li CC; Institute of Cellular and Organismic Biology, Academia Sinica, Taipei, Taiwan, ROC., Lin PY; Institute of Cellular and Organismic Biology, Academia Sinica, Taipei, Taiwan, ROC., Huang YP; Genomics Research Center, Academia Sinica, Taipei, Taiwan, ROC., Chang CF; Genomics Research Center, Academia Sinica, Taipei, Taiwan, ROC., You MF; Marine Research Station, Institute of Cellular and Organismic Biology, Academia Sinica, Jiaushi, Ilan, Taiwan, ROC., Chen JY; Marine Research Station, Institute of Cellular and Organismic Biology, Academia Sinica, Jiaushi, Ilan, Taiwan, ROC. zoocjy@gate.sinica.edu.tw.; The iEGG and Animal Biotechnology Center and the Rong Hsing Research Center for Translational Medicine, National Chung Hsing University, Taichung, Taiwan, ROC. zoocjy@gate.sinica.edu.tw.
Source: Npj antimicrobials and resistance [NPJ Antimicrob Resist] 2026 Apr 30; Vol. 4 (1). Date of Electronic Publication: 2026 Apr 30.
Publication Type: Journal Article
Journal Info: Publisher: Nature Portfolio Country of Publication: England NLM ID: 9918804282606676 Publication Model: Electronic Cited Medium: Internet ISSN: 2731-8745 (Electronic) Linking ISSN: 27318745 NLM ISO Abbreviation: NPJ Antimicrob Resist Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Antimicrobial peptide-induced inner membrane hyperpolarization is associated with antibiotic sensitization and attenuated MIC escalation in multidrug-resistant Gram-negative pathogens.
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  Data: <searchLink fieldCode="AU" term="%22Yeh+JC%22">Yeh JC</searchLink>; Marine Research Station, Institute of Cellular and Organismic Biology, Academia Sinica, Jiaushi, Ilan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Hazam+PK%22">Hazam PK</searchLink>; Marine Research Station, Institute of Cellular and Organismic Biology, Academia Sinica, Jiaushi, Ilan, Taiwan, ROC.; Faculty of Pharmaceutical Science, Assam down town University, Guwahati, Assam, India.<br /><searchLink fieldCode="AU" term="%22Lin+YY%22">Lin YY</searchLink>; Marine Research Station, Institute of Cellular and Organismic Biology, Academia Sinica, Jiaushi, Ilan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Chang+YC%22">Chang YC</searchLink>; Academia Sinica Cryo-EM Center, Academia Sinica, Taipei, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Selvaraj+SP%22">Selvaraj SP</searchLink>; Molecular and Biological Agricultural Science Program, Taiwan International Graduate Program, Academia Sinica, Taipei, Taiwan, ROC.; Graduate Institute of Biotechnology, National Chung Hsing University, Taichung, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Li+CC%22">Li CC</searchLink>; Institute of Cellular and Organismic Biology, Academia Sinica, Taipei, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Lin+PY%22">Lin PY</searchLink>; Institute of Cellular and Organismic Biology, Academia Sinica, Taipei, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Huang+YP%22">Huang YP</searchLink>; Genomics Research Center, Academia Sinica, Taipei, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Chang+CF%22">Chang CF</searchLink>; Genomics Research Center, Academia Sinica, Taipei, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22You+MF%22">You MF</searchLink>; Marine Research Station, Institute of Cellular and Organismic Biology, Academia Sinica, Jiaushi, Ilan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Chen+JY%22">Chen JY</searchLink>; Marine Research Station, Institute of Cellular and Organismic Biology, Academia Sinica, Jiaushi, Ilan, Taiwan, ROC. zoocjy@gate.sinica.edu.tw.; The iEGG and Animal Biotechnology Center and the Rong Hsing Research Center for Translational Medicine, National Chung Hsing University, Taichung, Taiwan, ROC. zoocjy@gate.sinica.edu.tw.
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  Data: <searchLink fieldCode="JN" term="%229918804282606676%22">Npj antimicrobials and resistance</searchLink> [NPJ Antimicrob Resist] 2026 Apr 30; Vol. 4 (1). <i>Date of Electronic Publication: </i>2026 Apr 30.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Portfolio%22">Nature Portfolio </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9918804282606676 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2731-8745 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2227318745%22">27318745 </searchLink><i>NLM ISO Abbreviation: </i>NPJ Antimicrob Resist <i>Subsets: </i>PubMed not MEDLINE
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              Text: 2026 Apr 30
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