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In vivo profiling of astrocyte secretome reveals brain-region specific regulatory networks in a mouse model of amyloid pathology.

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Title: In vivo profiling of astrocyte secretome reveals brain-region specific regulatory networks in a mouse model of amyloid pathology.
Authors: Jiang Q; Department of Neurology and Centre for Clinical Neuroscience, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, 400042, China.; Chongqing Key Laboratory of Ageing and Brain Diseases, Chongqing, 400042, China., Hu JN; Department of Neurology and Centre for Clinical Neuroscience, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, 400042, China.; Chongqing Key Laboratory of Ageing and Brain Diseases, Chongqing, 400042, China.; Shigatse Branch, Xinqiao Hospital, Army Medical University (Third Military Medical University), Tibet, 857012, China., Dong HM; Department of Cognitive Impairment Research, Chongqing Institute for Brain and Intelligence, Guangyang Bay Laboratory, Chongqing, 401336, China., Xin JY; Department of Neurology and Centre for Clinical Neuroscience, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, 400042, China.; Chongqing Key Laboratory of Ageing and Brain Diseases, Chongqing, 400042, China., Shi AY; Department of Neurology and Centre for Clinical Neuroscience, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, 400042, China.; Chongqing Key Laboratory of Ageing and Brain Diseases, Chongqing, 400042, China., Zeng GH; Department of Neurology and Centre for Clinical Neuroscience, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, 400042, China.; Chongqing Key Laboratory of Ageing and Brain Diseases, Chongqing, 400042, China., Liu J; Department of Neurology and Centre for Clinical Neuroscience, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, 400042, China. 17721056469@163.com.; Chongqing Key Laboratory of Ageing and Brain Diseases, Chongqing, 400042, China. 17721056469@163.com.; Department of Cognitive Impairment Research, Chongqing Institute for Brain and Intelligence, Guangyang Bay Laboratory, Chongqing, 401336, China. 17721056469@163.com., Wang YJ; Department of Neurology and Centre for Clinical Neuroscience, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, 400042, China. yanjiang_wang@tmmu.edu.cn.; Chongqing Key Laboratory of Ageing and Brain Diseases, Chongqing, 400042, China. yanjiang_wang@tmmu.edu.cn.
Source: Molecular neurodegeneration [Mol Neurodegener] 2026 May 23. Date of Electronic Publication: 2026 May 23.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101266600 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1750-1326 (Electronic) Linking ISSN: 17501326 NLM ISO Abbreviation: Mol Neurodegener Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: In vivo profiling of astrocyte secretome reveals brain-region specific regulatory networks in a mouse model of amyloid pathology.
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  Data: <searchLink fieldCode="AU" term="%22Jiang+Q%22">Jiang Q</searchLink>; Department of Neurology and Centre for Clinical Neuroscience, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, 400042, China.; Chongqing Key Laboratory of Ageing and Brain Diseases, Chongqing, 400042, China.<br /><searchLink fieldCode="AU" term="%22Hu+JN%22">Hu JN</searchLink>; Department of Neurology and Centre for Clinical Neuroscience, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, 400042, China.; Chongqing Key Laboratory of Ageing and Brain Diseases, Chongqing, 400042, China.; Shigatse Branch, Xinqiao Hospital, Army Medical University (Third Military Medical University), Tibet, 857012, China.<br /><searchLink fieldCode="AU" term="%22Dong+HM%22">Dong HM</searchLink>; Department of Cognitive Impairment Research, Chongqing Institute for Brain and Intelligence, Guangyang Bay Laboratory, Chongqing, 401336, China.<br /><searchLink fieldCode="AU" term="%22Xin+JY%22">Xin JY</searchLink>; Department of Neurology and Centre for Clinical Neuroscience, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, 400042, China.; Chongqing Key Laboratory of Ageing and Brain Diseases, Chongqing, 400042, China.<br /><searchLink fieldCode="AU" term="%22Shi+AY%22">Shi AY</searchLink>; Department of Neurology and Centre for Clinical Neuroscience, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, 400042, China.; Chongqing Key Laboratory of Ageing and Brain Diseases, Chongqing, 400042, China.<br /><searchLink fieldCode="AU" term="%22Zeng+GH%22">Zeng GH</searchLink>; Department of Neurology and Centre for Clinical Neuroscience, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, 400042, China.; Chongqing Key Laboratory of Ageing and Brain Diseases, Chongqing, 400042, China.<br /><searchLink fieldCode="AU" term="%22Liu+J%22">Liu J</searchLink>; Department of Neurology and Centre for Clinical Neuroscience, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, 400042, China. 17721056469@163.com.; Chongqing Key Laboratory of Ageing and Brain Diseases, Chongqing, 400042, China. 17721056469@163.com.; Department of Cognitive Impairment Research, Chongqing Institute for Brain and Intelligence, Guangyang Bay Laboratory, Chongqing, 401336, China. 17721056469@163.com.<br /><searchLink fieldCode="AU" term="%22Wang+YJ%22">Wang YJ</searchLink>; Department of Neurology and Centre for Clinical Neuroscience, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, 400042, China. yanjiang_wang@tmmu.edu.cn.; Chongqing Key Laboratory of Ageing and Brain Diseases, Chongqing, 400042, China. yanjiang_wang@tmmu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101266600%22">Molecular neurodegeneration</searchLink> [Mol Neurodegener] 2026 May 23. <i>Date of Electronic Publication: </i>2026 May 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101266600 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1750-1326 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217501326%22">17501326 </searchLink><i>NLM ISO Abbreviation: </i>Mol Neurodegener <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s13024-026-00956-y
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            – D: 23
              M: 05
              Text: 2026 May 23
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              Y: 2026
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